tag:blogger.com,1999:blog-18840351707851800342024-02-19T02:56:24.059-08:00The Genome ReportThis is a forum for news and views on human genomics. Many of the edited posts are written by undergraduate biology students and selected high school students.Unknownnoreply@blogger.comBlogger5125tag:blogger.com,1999:blog-1884035170785180034.post-2380960361721978212009-08-16T10:37:00.000-07:002009-08-16T11:04:52.759-07:00INDELS, gene expression and hereditary cancer
<!--[if gte mso 9]> Normal 0 0 1 605 3453 28 6 4240 11.1282 <![endif]--><!--[if gte mso 9]> 0 0 0 <![endif]--> <!-- /* Font Definitions */ @font-face {font-family:"Times New Roman"; panose-1:0 2 2 6 3 5 4 5 2 3; mso-font-charset:0; mso-generic-font-family:auto; mso-font-pitch:variable; mso-font-signature:50331648 0 0 0 1 0;} /* Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1884035170785180034.post-6659202460188952752009-07-21T21:07:00.000-07:002009-07-31T10:37:10.236-07:00Soon, we will all be VOUS – The need for a cancer oriented ENCODE programThe BRCA1/BRCA2 test is now considered the standard of care for identifying breast and ovarian cancer risk. Indeed, women who have been tested for BRCA1/BRCA2 status must view the current discourse on the possible implications of personalized genetic medicine with incredulity. It is very clear that women who inherit a dysfunctional form of the BRCA1 or BRCA2 gene have a much higher risk of Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1884035170785180034.post-87588981062560181302009-07-14T19:47:00.000-07:002009-07-15T14:49:16.980-07:00How do mutations arise in RNA viruses?As we understand more about the human genome, it becomes equally important to understand its relationship with the genomic environment. In the case of RNA viruses such as SARS, Hepatitis C or Influenza, an inappropriate interaction with a viral genome can result in death. The human genome defends itself by to engineering specific immunological factors (T cells, antibodies) that selectively Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1884035170785180034.post-33001296275988544642009-07-10T07:04:00.000-07:002009-07-15T08:19:50.331-07:00Novel connections between the “old” protein world and the “ new” RNA world.Amidst the increasing attention given to the economical sequencing of the human genome, one inconvenient truth remains largely ignored. Virtually all of biomedical science and pharmaceutical industry has focused on merely 2% of the genome, the segment of the genome that encodes proteins. Until recently the other 98% had been somewhat famously described as Junk. However, it is now clear thatUnknownnoreply@blogger.com0tag:blogger.com,1999:blog-1884035170785180034.post-11241757425397580862009-06-28T21:07:00.000-07:002009-08-06T10:17:55.658-07:00A Call for a Grass Roots Genomics MovementDicer and Familial Lung CancerThe recent report in Science that mutations in the Dicer gene underlie Familial Pleuropulmonary Blastoma has all the hallmarks of a classic scientific discovery. Perseverance, dedication, compassion and brilliant scientific insight combined to yield a spectacular advance in cancer genetics. Dicer is an enzyme that is essential to the expression of a new class of Unknownnoreply@blogger.com0